Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
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چکیده
منابع مشابه
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
sorLA (Sorting protein-related receptor) is a type-1 membrane protein of unknown function that is expressed in neurons. Its homology to sorting receptors that shuttle between the plasma membrane, endosomes, and the Golgi suggests a related function in neuronal trafficking processes. Because expression of sorLA is reduced in the brain of patients with Alzheimer's disease (AD), we tested involvem...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2005
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0503689102